alternanthera sessilis red

The extraction of pancreatic insulin was adopted from Portha et al. (Alternanthera sessilis) aka Mukunuwenna, Dwarf Copperleaf, Red Carpet Weed Perennial Full sun - part shade Edible Prefers shallow water Small white sessile spike flowers If it is in season and available in WA it is in stock. 413. The mixture was filtered, and the filtrate was concentrated by the rotary evaporator, yielding the hexane fraction (ASHXF). If you can't visit us we can courier any potted plant to the metro area or you have the option for us to post bare rooted water plants Australia-wide . Stems are smooth and reddish purple. As shown in Figure 6, ASEAF did not significantly alter the liver triglyceride content of the diabetic rats when compared to the negative control group (). Department of Physiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia, Evidence-Based Complementary and Alternative Medicine, Data shown are the calculated index values and are presented as mean, Absence of amino acid but presence of secondary amine, Absence of carotenoid; presence of terpenoids, J. E. Shaw, R. A. Sicree, and P. Z. Zimmet, “Global estimates of the prevalence of diabetes for 2010 and 2030,”, I. S. Ismail, W. M. Wan Nazaimoon, W. B. Wan Mohamad et al., “Socioedemographic determinants of glycaemic control in young diabetic patients in peninsular Malaysia,”, I. M. Al-Masri, M. K. Mohammad, and M. O. Tahaa, “Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine,”, J. Yin, H. Xing, and J. Ye, “Efficacy of berberine in patients with type 2 diabetes mellitus,”, T. Subhashini, B. Krishnaveni, and C. Srinivas Reddy, “Anti-inflammatory activity of the leaf extract of, M. Surendra Kumar, G. Silpa Rani, S. L. V. V. S. N. K. Swaroop Kumar, and N. Astalakshmi, “Screening of aqueous and ethanolic extracts of aerial parts of, S. George, S. V. Bhalerao, E. A. Lidstone et al., “Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells,”, A. Borah, R. N. S. Yadav, and B. G. Unni, “In vitro antioxidant and free radical scavenging activity of. Furthermore, lipolysis is not suppressed under insulin resistance, producing and releasing more FFA into the circulation. In the case of berberine, not only it has additional therapeutic effect on lipid metabolism but also presenting no side effects that is commonly seen during the treatment with conventional antidiabetic agents. The aerial parts of ASR were dried in the oven at 40°C and crushed into powder. This cultivar is more commonly found in Malaysia and Singapore than the wild type. Subsequently, 2 g/kg glucose solution (dissolved in distilled water) was administered to all the diabetic rats. Briefly, the diabetic rats were divided into 5 groups () and were fasted overnight for 16 hours. The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. The combination of high fat diet and low dose streptozotocin (STZ) has been commonly used to induce obese type 2 diabetes in the rats [10]. True seed (often shed enclosed within a single-seeded utricle and perianth) Seed identification features Size Useful Tropical Plants Database 2014 by 0.2 g of thawed pancreas portion was placed in a centrifuge tube containing 5.0 mL of ice-cold acid-alcohol solution. Copyright © 2013 Kok Keong Tan and Kah Hwi Kim. The index values before and after 250 mg/kg ASEAF oral administration were shown. The top layer is the plasma sample. We demonstrated that ASEAF possesses antihyperglycemic effect, antitriglyceridemic effect, and pancreatic protective effect in obese type 2 diabetic rats. Masoprocol inhibits hormone-sensitive lipase (HSL) via, possibly, the dephosphorylation of HSL by increasing phosphatase activity [18]. The authors declare that there is no conflict of interests. Alternanthera is a genus of flowering plants in the family Amaranthaceae. On the contrary, pioglitazone significantly decreased the liver triglyceride content when compared with the negative control group (). Thence, the total SOD activity was preserved. Persons suffering from night blindness (Nyctalopia) can eat the raw flower of sessilis continuously will feel the difference in their eyesight. [10] with slight modification. Rats with blood glucose level more than 16.5 mmol/L were selected for subsequent experiment. It could be considered a ground cover in many circumstances. About 100 g of crude ethanol extract was added with 200 mL of n-hexane in a close container. [4] showed that berberine has similar antihyperglycemic potency to metformin (a common antidiabetic agent) and possessed antihypertriglyceridemic effect which is not seen in metformin. Ken Fern, The cultivar is named as Alternanthera sessilis Red , and it is often called as Hongtyang wu (Chinese) by the Malaysian, Singaporean, and Taiwanese. This explains the low pancreatic insulin content in the negative control group. On day 15, the overnight fasted (16 hours) rats were injected with 40 mg/kg of streptozotocin (STZ) intraperitoneally. Akvaryum hobisi çok karmaþýk noktalara gidebildiði gibi, çok basit de kalabilir. Description and Ethnobotany. Alternanthera Sessilis or known as Ponnanganni is an aquatic plant that belongs to amarantheceae family and grown in tropical and subtropical regions. Stems. Chronic FFA-induced insulin hypersecretion reduces insulin biosynthesis in the pancreatic β cells [22]. [13], 0.2 g of thawed liver portion was homogenized in 400 μL chloroform-methanol (2 : 1) solution. After treatment with 30 mg/kg pioglitazone, the plasma TG level, and plasma FFA level of the treated rats decreased 52.21% and 35.57%, respectively. How Alternanthera Sessilis is effective for various diseases is listed in repertory format. The mixture was subjected to sonication for 15 minute at room temperature. Medicinal properties are low. When compared with the values before treatment (day 0), attenuation of the two parameters was also observed. This is because at a similar level of insulin in the blood of the diabetic rats in different groups, the fasting BGL of the treatment groups (ASEAF treated and pioglitazone treated) were lower, indicating that the decrease in BGL was brought about by the enhanced insulin action. As can be seen in Figure 7, both ASEAF and pioglitazone increased the pancreatic insulin content of the diabetic rats (). Reviewer/s: Arisdason, W., Gunaga, S. & Narasimhan, D. Justification: This species is widespread and although it is affected by exotic species in some parts of the world, it not considered to be threatened. Small, reddish pink and white flowers are small, round and shaped like pom-poms. Indeed, the plasma triglyceride (TG) level and plasma free fatty acid (FFA) level of the pioglitazone-treated group and ASEAF-treated group were significantly lower than the negative control group () as shown in Figures 4 and 5, respectively. The pancreatic insulin content was expressed as μg/mg wet tissue. With the undesirable side effects of the antidiabetic agents found in the market nowadays, traditional medicine serves an important role in the discovery of new antidiabetic agent with lesser and fewer side effects. Flowers. Elongated leaves are oblong to lance-shaped (1-8 x 0.2-2 cm). Distribution in Canada. Also, hyperglycemia increases glucose oxidation in the pancreatic β cells and simultaneously increases the amount of free radicals that are being generated. The liver triglyceride content was expressed as mg/g wet tissue. Spraying reagents contain chemicals that bind to specific functional group of a compound and producing colors that allows the researcher to identify the presence of a specific class of compound. Plants of the genus may be known generally as joyweeds, or Joseph's coat. Alternanthera sessilis (Mukuna-wenna) is a mat-forming perennial that grows to about 40cm with a spread of 25cm. The top layer is the serum sample. Uses, Benefits, Cures, Side Effects, Nutrients in Alternanthera Sessilis. Alternanthera sessilis Red ethyl acetate fraction (ASEAF) was found to possess the most potent antihyperglycemic effect through oral glucose tolerance test. The induction of diabetes was done according to Srinivasan et al. To get this best colours out of this plant, high light is required which can often make this tricky to grow. Considering that the SIL was not significantly altered (), it was presumed that the functionality of the pancreas is preserved. The TLC plate was then allowed to develop in a chamber saturated with ethyl acetate and chloroform in the ratio of 6 : 4 (ethyl acetate : chloroform). Berberine is an inhibitor of dipeptidyl peptidase IV [3]. Also, isolation and identification of the bioactive compound(s) that responsible for the antidiabetic effect are in progress. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Plasma FFA level has been known to cause hepatic insulin resistance [21]. The pancreas and liver were harvested after the rats being sacrificed through cervical dislocation. One kilogram of the powder was extracted with 3 L of 95% ethanol at room temperature for three days. Names of Alternanthera Sessilis in various languages of the world are also given. demonstrated that (+)-camphene, which is a type of terpenoids, possessed powerful antioxidant effect [24], or (2) ASEAF improves peripheral insulin sensitivity which reduces blood glucose concentration. ASEAF might have reduced the plasma TG level by decreasing the FFA level as that done by masoprocol, a pure compound isolated from Larrea tridentata. Seemai Ponnangkanni, which is red in color, is often grown for its beauty. Paired and unpaired Student’s t-test was conducted using SPSS 17.0. List of various diseases cured by Alternanthera Sessilis. B. Jenkins, E. A. Daley, D. J. Chisholm, and L. H. Storlien, “Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats,”, G. Boden, P. She, M. Mozzoli et al., “Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-, L. C. Bollheimer, R. H. Skelly, M. W. Chester, J. D. McGarry, and C. J. Rhodes, “Chronic exposure to free fatty acid reduces pancreatic, J. Graßmann, “Terpenoids as plant antioxidants,”. Alternanthera Sessilis has the greatest ability to improve the vision. Alternanthera Sessilis. Prevalence of diabetes mellitus in Malaysia is increasing alarmingly. Alternanthera sessilis ‘Red’ Family: Amaranthaceae: Common Name: Red Sessile Joyweed, Red Carpet Weed, Bayam Keremak Merah, Red Ceylon Spinach: Origin: - Leaf Colour: Reddish Purple: Flower Colour: Small Reddish Pink and White: Propagation: Seed and stem cutting: Description: Three fractions (hexane, ethyl acetate, and water) were obtained from the crude ethanol extract of Alternanthera sessilis Red. Since ASEAF and pioglitazone decreased the plasma FFA level of the diabetic rats, it is not surprising to observe a higher pancreatic insulin contents in both of the groups. Kok Keong Tan, Kah Hwi Kim, "Alternanthera sessilis Red Ethyl Acetate Fraction Exhibits Antidiabetic Potential on Obese Type 2 Diabetic Rats", Evidence-Based Complementary and Alternative Medicine, vol. The low dose of STZ injected to the insulin resistant rats produced frank hyperglycemia which mimics human type 2 diabetes. Introduction. The solvent was removed using RV10 rotary evaporator (IKA, Guangzhou), and the resulting residue was the crude ethanolic extract (112.5 g). In India, in the states of Bengal and Bihar, root extract of this herb is used as a natural remedy for serious eye diseases such as cataract, hazy vision, burning eyes, watery eyes and myopia. The superoxide dismutase activity was expressed as unit/mg wet tissue. Alternanthera Sessilis. In the two-week study, 30 mg/kg pioglitazone (a potent insulin sensitizer) was used as a positive control, whereas the negative control group consisted of diabetic rats given with 2 mL/kg of 1% CMC (the vehicle). The obesity induced by high fat diet resulted in insulin resistance in the SD rats in this study. After 30 minutes, the blood glucose level of the diabetic rats was measured using a glucometer (AccuChek Advantage). Amaranthaceae. B. Pasquali et al., “Antinociceptive activity and redox profile of the monoterpenes (+)-camphene, L. A. H. Borg, E. Cagliero, S. Sandler, N. Welsh, and D. L. Eizirik, “Interleukin-1, J. V. Hunt, C. C. T. Smith, and S. P. Wolff, “Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose,”. All fractions and glibenclamide were dissolved in 1% carboxymethylcellulose. Rather, it improved the peripheral insulin sensitivity. The plant occurs around the world. The leaves are used as a vegetable. 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